Granisetron hydrochloride ( BRL 43694 )

产品货号. M10289 CAS No. 107007-99-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Granisetron hydrochloride
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Granisetron Hcl(BRL 43694A) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.
产品描述

Granisetron Hcl(BRL 43694A) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. IC50 Value: 17uM (GR reduced 5-HT-evoked contractions)
同义词

BRL 43694
通路

Endocrinology/Hormones
靶点

5-HT Receptor
受体

5-HT
研究领域

Neurological Disease
适应症

——

CAS Number

107007-99-8
分子量

348.87
分子式

C18H25ClN4O
纯度

>98%(HPLC)
溶解度

Ethanol: 1 mg/mL (2.86 mM); Water: 70 mg/mL (200.64 mM); DMSO: 1 mg/mL (2.86 mM)
SMILES

Cl.CN1N=C(C(=O)NC2CC3CCCC(C2)N3C)C2=CC=CC=C12
化学全称

——

1.Turvill JL, et al. Br J Pharmacol. 2000 Jul;130(5):1031-6.

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